Azumanga Daioh

The main cast of Azumanga Daioh consists of six schoolgirls and two of their teachers. Secondary characters include Kimura-sensei, a creepy male teacher with an unhealthy obsession with teenage girls, and Kaorin, a classmate with a crush on Sakaki.

Chiyo Mihama

A child prodigy, who is considered amazingly cute by the other characters. Through her, the series humorously explores the consequences of skipping five grades to tenth grade. She is a target of jealousy due to her intelligence and wealthy family.

Tomo Takino

An extremely energetic and competitive girl, despite being nonathletic and a slacker. Tomo's character is extremely impulsive and rarely considers the consequences of anything. She is a selfproclaimed Lupin III fanatic.

Koyomi "Yomi" Mizuhara

A grade-school friend and Tomo's general antagonist, Yomi as she is commonly known, is the title's voice of reason and straight man, carrying herself as the most mature and serious of the group. Though smart and athletic, she is constantly dissatisfied with herself due to her weight and is always trying various diets in an effort to become thinner.

Sakaki

A tall, soft-spoken girl uncomfortable with her height and busty physique. Her reticence is misinterpreted as cool. She is naturally athletic but she has no real interest in sports, an emotionally sensitive person who holds a secret longing for cute things and she loves cats.

Ayumu "Osaka" Kasuga

More popularly known by her nickname Osaka, Ayumu is a transfer student from Osaka. She has a mind that works differently than other people, prone to daydreaming, absentmindedness, and non-sequiturs, but exceptional at answering very specific types of riddles.

Kagura

She joins Yukari's class in the second year. Originally in Nyamo's class and with little success in studies, she devotes her time to the swim team but is an all-around good athlete. She is genuinely nice to her classmates but is competitive and has a slight obsession with Sakaki. She is also sensitive and prone to tears when she doesn't perform as well as she wants to, or at the thought of parting with her friends.

Yukari Tanizaki

The girls' English and homeroom teacher (class 3), with very unconventional methods and a close relationship with the class. She can be moody and, like Tomo, is incredibly impulsive and has a tendency not to think things through. Yukari has a rivalry/friendship with Minamo and attempts to prove that she is the superior teacher.

Minamo "Nyamo" Kurosawa

A gym teacher at the girls' school. She is an old high school friend and rival of Yukari, who occasionally refers to her by an old nickname of Nyamo (にゃも ,Nyamo?), despite Minamo's wishes to the contrary. Popular with the students, Minamo is nicer and in greater control of herself than Yukari, but, in moments of weakness, Minamo has proven that she can be just as vulnerable to losing control as is Yukari.